Over the past two decades, studies regarding the production of new drugs, systems and imaging techniques have been widely performed upon animal models. Conducting in vivo experiments upon live animals is one of the main requirements of these investigations since they facilitate the observation and tracking of drugs distribution and other biological phenomena which are not visible in vitro.
Fluorescence Molecular Imaging Systems were firstly introduced by Garofalakis and his colleagues. The first generation of this imaging system was designed for Non-contact Fluorescence Molecular Tomography.